MSM Based Amino Blend (Cartilage Research)

Product | MSM Based Amino Blend (Cartilage Research)

MSM Based Amino Blend (Cartilage Research)

Compound	CAS#	Chemical Formula	Net Content/mL
N-Acetyl-D-Glucosamine (NAG)	7512-17-6	C₈H₁₅NO₆	150 mg/mL
Chondroitin Sulfate	CID 24766	Polymer	40 mg/mL
Methylsulfonylmethane (MSM)	67-71-0	C₂H₆O₂S	40 mg/mL

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What is MSM Based Amino Blend (Cartilage Research)?

MSM Based Amino Blend (Cartilage Research) is a three-component research solution of N-acetyl-D-glucosamine (NAG), chondroitin sulfate and methylsulfonylmethane (MSM). Despite the “amino blend” name, none of the three components is an amino acid: NAG is an amino sugar, chondroitin sulfate is a sulfated glycosaminoglycan polymer, and MSM is an organosulfur compound. NAG is the largest component at 150 mg/mL.

MSM (dimethyl sulfone) is the fully oxidized end of the dimethyl sulfide series (Butawan et al., 2017), NAG is an N-acetylated amino sugar, and chondroitin sulfate is a sulfated polysaccharide with no single molecular structure. Together they give a defined amino sugar, glycosaminoglycan and organosulfur mixture.

Batch-verified at Modern Aminos, it is supplied in one laboratory format, a 20 mL vial. The carrier is a water-based solution with benzyl alcohol (1%) as the preservative. Per-mL composition:

N-Acetyl-D-Glucosamine (NAG): 150 mg/mL
Chondroitin Sulfate: 40 mg/mL
Methylsulfonylmethane (MSM): 40 mg/mL

Laboratories building metabolic panels often place it next to public reference listings such as ITPP (Myo-inositol trispyrophosphate).

Chemical and Molecular Data for MSM Based Amino Blend (Cartilage Research)

Compound Name	MSM Based Amino Blend (Cartilage Research)
Research Category	MSM, NAG & Chondroitin Blend; 3-component research solution
Quantity / Formats Offered	20 mL Vial (solution)
Composition per mL	N-Acetyl-D-Glucosamine (NAG) 150 mg/mL \| Chondroitin Sulfate 40 mg/mL \| Methylsulfonylmethane (MSM) 40 mg/mL
Carrier / Excipients	Water-based solution with benzyl alcohol (1%) as the preservative
Synonyms / Alt Names	MSM Based Amino Blend, MSM blend, MSM amino blend research solution, A-009

Each component is identified below from its PubChem record; amounts are per mL of finished solution, and salt forms are listed as weighed.

N-Acetyl-D-Glucosamine (NAG) (150 mg/mL)

PubChem CID	439174
CAS Number	7512-17-6
ChEBI	CHEBI:506227
Chemical Formula	C₈H₁₅NO₆
Molecular Weight	221.21 g/mol
InChIKey	OVRNDRQMDRJTHS-RTRLPJTCSA-N

Chondroitin Sulfate (40 mg/mL)

Chondroitin sulfate is a polymer of varying chain length and sulfation, so no single formula, molecular weight or CAS number applies. PubChem’s CID 24766 represents one sulfated disaccharide repeating unit.

Methylsulfonylmethane (MSM) (40 mg/mL)

PubChem CID	6213
CAS Number	67-71-0
ChEBI	CHEBI:9349
Chemical Formula	C₂H₆O₂S
Molecular Weight	94.14 g/mol
InChIKey	HHVIBTZHLRERCL-UHFFFAOYSA-N

What are the Mechanisms of Action?

The pathway chemistry behind MSM Based Amino Blend (Cartilage Research) in laboratory research includes:

Organosulfur chemistry: Methylsulfonylmethane (dimethyl sulfone, DMSO₂) is the fully oxidized member of the dimethyl sulfide, dimethyl sulfoxide and dimethyl sulfone series (Butawan et al., 2017); sulfur accounts for about 34% of its molecular weight (32.06 of 94.14 g/mol, PubChem CID 6213), and it occurs as a product of microbial–mammalian co-metabolism (He & Slupsky, 2014).
Amino sugar: N-acetyl-D-glucosamine is a 2-acetamido-2-deoxy-D-hexose (ChEBI:506227); its acetamido group at C-2 distinguishes it from glucose, and it is the major component (150 mg/mL) of the MSM blend.
Sulfated glycosaminoglycan: Chondroitin sulfate is a polymer, so no single structure or molecular weight applies; PubChem represents a sulfated disaccharide repeating unit (CID 24766, C₁₃H₂₁NO₁₅S, 463.37 g/mol for that unit).

Component	Amount per mL	Pathway role	Source
NAG	150 mg/mL	N-acetylated amino sugar	PubChem
Chondroitin Sulfate	40 mg/mL	Sulfated glycosaminoglycan polymer	PubChem
MSM	40 mg/mL	Oxidized organosulfur (dimethyl sulfone)	Butawan et al., 2017

What Does Published Research Show for MSM Blend?

Published reviews on the components of MSM Based Amino Blend (Cartilage Research) center on their pathway biochemistry:

Methylsulfonylmethane Chemistry (Review, PMC): Butawan and colleagues reviewed MSM as the oxidized end of the DMSO series (Butawan et al., 2017).
Dimethyl Sulfone Metabolic Origin (Review): He and Slupsky described dimethyl sulfone as a product of microbial and mammalian co-metabolism of methanethiol and dimethyl sulfide (He & Slupsky, 2014).
Chemical Directory & Structure Verification (PubChem): NAG CID 439174; MSM CID 6213. Identifiers on this page were checked against these records on October 8, 2026.
Analytical Quality: Why chromatographic testing matters for reference materials is covered in Modern Aminos’ note on HPLC testing.

How does MSM Blend compare to other compounds?

To place MSM Blend among related research materials, the table compares it with other solutions and references available at Modern Aminos:

Compound / Reference	Primary Target Class	Core Mechanism of Action	Research Focus & Profile
MSM Based Amino Blend (Cartilage Research)	Amino sugar + GAG + organosulfur	NAG, chondroitin sulfate and MSM per mL	Organosulfur and amino sugar chemistry
BCAA Based Amino Blend	Amino acids	Nine amino acids including branched-chain amino acids	Amino acid metabolism panels
ITPP (Myo-inositol trispyrophosphate)	Inositol phosphate	Myo-inositol trispyrophosphate, a single defined molecule	Allosteric effector chemistry

Frequently Asked Questions (FAQs)

1. Where can I buy MSM Based Amino Blend (Cartilage Research) with lot certificates?

MSM Based Amino Blend (Cartilage Research) is available at Modern Aminos as a 20 mL research solution (SKU A-009). FreedomDiagnostics reported lot BX-A-D9J2 on 9/12/2026 with identity confirmed by LC-MS (N-acetyl-glucosamine and methylsulfonylmethane), a clear liquid appearance, and no detectable microbial DNA by PCR. If you want to buy MSM Based Amino Blend as a documented reference material, each certificate is in the Certificate of Analysis tab.

2. What does MSM Blend contain per mL?

Per the Modern Aminos manufacturing formula (SKU A-009), each mL contains N-Acetyl-D-Glucosamine (NAG) 150 mg/mL; Chondroitin Sulfate 40 mg/mL; Methylsulfonylmethane (MSM) 40 mg/mL. Carrier: water-based solution with benzyl alcohol (1%) as the preservative.

3. Is MSM Blend a peptide or a supplement?

No. None of its 3 components is a peptide; it is a solution of free amino acids and small molecules supplied for laboratory research, not as a supplement.

4. What are the PubChem identifiers for the components?

NAG: CID 439174 (CAS 7512-17-6); Chondroitin Sulfate: polymer, no single CID; MSM: CID 6213 (CAS 67-71-0). The full identifier tables are in the Chemical and Molecular Data section above.

5. What is MSM chemically?

MSM is methylsulfonylmethane, also called dimethyl sulfone or DMSO₂ (PubChem CID 6213, CAS 67-71-0, C2H6O2S, 94.14 g/mol). It is the oxidation product of dimethyl sulfoxide (Butawan et al., 2017).

6. Does the MSM blend contain amino acids?

No. The manufacturing formula lists N-acetyl-D-glucosamine, chondroitin sulfate and MSM only; “amino blend” is the product family name. NAG is an amino sugar, not an amino acid.

7. Why is there no single CAS or molecular weight for chondroitin sulfate?

Chondroitin sulfate is a polymer of varying chain length and sulfation, so no single structure applies. PubChem’s record (CID 24766) represents one sulfated disaccharide unit, and its 463.37 g/mol describes that unit only.

8. Does the lot certificate detect chondroitin sulfate?

The LC-MS identity list on lot BX-A-D9J2 names N-acetyl-glucosamine and methylsulfonylmethane. Chondroitin sulfate, a polymer listed in the manufacturing formula at 40 mg/mL, is not named on that certificate.

9. How does the MSM blend compare to single-molecule references?

It is a mixture of three chemically different classes, whereas a reference such as ITPP (Myo-inositol trispyrophosphate) is a single defined molecule. Use the blend where the combined amino sugar, glycosaminoglycan and organosulfur matrix is the object of study.

10. What format is MSM Blend supplied in?

One format: a 20 mL vial of solution at the per-mL amounts listed above. The vial label lists the per-mL ingredients, and the Certificate of Analysis tab lists the certificates for the current format.

11. How does Modern Aminos verify MSM Blend?

The FreedomDiagnostics certificate for lot BX-A-D9J2 lists identity by LC-MS and a PCR-based microbial screen (no detectable microbial DNA). It does not report purity or per-component quantity, so this page makes no content claim. For background on chromatographic testing, see why HPLC testing matters.

12. How should MSM Blend be stored in the lab?

Keep the sealed vial cool, dry and away from light, and follow the label on each lot. No storage temperature is printed on the label or the certificates, so this page does not state one.

DISCLAIMER: All compounds and research materials supplied by Modern Aminos are intended exclusively for in vitro laboratory research by qualified professionals. They are not medicinal products and have not been authorised by the European Medicines Agency or any national competent authority for human or veterinary use. They are not foods, food supplements, cosmetics or medical devices. Products must not be administered to humans or animals by any route and must not be used for in vivo experimentation or any other non-laboratory purpose. We will refuse or cancel orders, and may close accounts, where there is any indication of human or animal use. By purchasing, you confirm that products will be used only in a controlled laboratory environment by appropriately qualified personnel, in line with all applicable laws.