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Product | L-Carnitine (20ML)

L-Carnitine (20ML)

L-Carnitine (20ML) research solution at 600mg/ml for laboratory mitochondrial fatty acid transport, beta-oxidation, and metabolic flexibility studies.

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What is L-Carnitine (20ML)?

L-Carnitine (20ML) is a 600 mg/mL research solution of L-carnitine (levocarnitine), the (R)-enantiomer of 3-hydroxy-4-(trimethylazaniumyl)butanoate. L-carnitine is not an amino acid in the protein-building sense: it is a quaternary ammonium hydroxy acid made from lysine-derived 6-N-trimethyllysine (Vaz & Wanders, 2002) and present as a zwitterion (inner salt).

Its role in research is the carnitine shuttle: CPT1 forms acylcarnitine at the outer mitochondrial membrane, the acylcarnitine crosses the inner membrane, and CPT2 regenerates acyl-CoA in the matrix, with malonyl-CoA inhibition of CPT1 as the control point (McGarry & Brown, 1997). Carnitine acetyltransferase links the free carnitine pool to acetyl-CoA (Ramsay & Naismith, 2003).

Buy L-Carnitine that is batch-verified at Modern Aminos and supplied in a 20 mL Amber vial. The carrier is a water-based solution with benzyl alcohol (1%) as the preservative with a Per-mL composition of 600 mg/mL.

Laboratories building metabolic panels often place it next to public reference listings such as DADA (Diisopropylamine Dichloroacetate).

Chemical and Molecular Data for L-Carnitine (20ML)

Compound Name L-Carnitine
Research Category Carnitine Shuttle Substrate
Quantity / Formats Offered 600 mg/mL (20 mL Vial)
Synonyms / Alt Names L-Carn, levocarnitine
PubChem CID 10917
CAS Number 541-15-1
ChEBI CHEBI:16347
Chemical Formula C7H15NO3
Molecular Weight 161.20 g/mol
UNII 0G389FZZ9M
Exact Mass 161.1052 Da
IUPAC Name (3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate
InChIKey PHIQHXFUZVPYII-ZCFIWIBFSA-N
Carrier / Excipients Aqueous solution w/ 1% benzyl alcohol (preservative)

What are the Mechanisms of Action?

The pathway chemistry behind L-Carnitine (20ML) in laboratory research includes:

  • Carnitine shuttle: L-Carnitine accepts long-chain acyl groups from acyl-CoA through carnitine palmitoyltransferase 1 (CPT1) at the outer mitochondrial membrane; the acylcarnitine crosses the inner membrane, and CPT2 regenerates acyl-CoA in the matrix, with malonyl-CoA inhibition of CPT1 as the control point (McGarry & Brown, 1997). Endogenous L-carnitine is built from 6-N-trimethyllysine released from methylated proteins (Vaz & Wanders, 2002).
  • Acetyl transfer: Carnitine acetyltransferase moves acetyl groups reversibly between acetyl-CoA and L-carnitine, forming acetyl-L-carnitine and buffering the mitochondrial acetyl-CoA/CoA ratio (Ramsay & Naismith, 2003).
Carnitine form PubChem record Relationship In this product?
L-Carnitine CID 10917, CAS 541-15-1 Free acyl carrier for CPT1/CPT2 (McGarry & Brown, 1997) Yes, 600 mg/mL
Acetyl-L-Carnitine HCl CID 2733928, CAS 5080-50-2 Acetyl ester formed by carnitine acetyltransferase (Ramsay & Naismith, 2003) No

What Does Published Research Show for L-Carnitine?

Published reviews on the components of L-Carnitine (20ML) center on their pathway biochemistry:

  • Carnitine Palmitoyltransferase System (Review): McGarry and Brown traced the CPT system from the original carnitine-shuttle concept to the molecular analysis of CPT1 and CPT2, including malonyl-CoA control of CPT1 (McGarry & Brown, 1997).
  • Carnitine Biosynthesis (Review, PMC): Vaz and Wanders described the four enzymatic steps from 6-N-trimethyllysine to L-carnitine, ending at γ-butyrobetaine hydroxylase (Vaz & Wanders, 2002).
  • Carnitine Acetyltransferase Structure (Review): Ramsay and Naismith summarized the crystal structures and catalytic mechanism of carnitine acetyltransferase (Ramsay & Naismith, 2003).
  • Chemical Directory & Structure Verification (PubChem): L-Carnitine CID 10917. Identifiers on this page were checked against these records on October 8, 2026.
  • Analytical Quality: Why chromatographic testing matters for reference materials is covered in Modern Aminos’ note on HPLC testing.

How does L-Carnitine compare to other compounds?

To buy L-Carnitine and compare it to related research materials, the table shows other solutions and references available at Modern Aminos:

Compound / Reference Primary Target Class Core Mechanism of Action Research Focus & Profile
L-Carnitine (20ML) Carnitine shuttle Free L-carnitine at 600 mg/mL CPT1/CPT2 acyl-transport assays
L-Carnitine / L-Arginine Based Amino Blend Carnitine + urea-cycle amino acids L-carnitine 400 with L-arginine HCl and L-ornithine HCl Carnitine plus arginase branch
L-Carnitine / CDP Choline Based Amino Blend Carnitine + CDP-choline L-carnitine 200 with CDP-choline 300 mg/mL Lipid transport and phosphatidylcholine synthesis
DADA (Diisopropylamine Dichloroacetate) PDK inhibitor Inhibits pyruvate dehydrogenase kinase Pyruvate vs fatty-acid fuel entry

Frequently Asked Questions (FAQs)

1. Where can I buy L-Carnitine (20ML) with lot certificates?

L-Carnitine (20ML) is available at Modern Aminos as a 20 mL research solution (SKU A-010). If you want to buy L-Carnitine as a documented reference material, each certificate is in the Certificate of Analysis tab.

2. What does L-Carnitine contain per mL?

Per the Modern Aminos manufacturing formula (SKU A-010), each mL contains L-Carnitine 600 mg/mL. Carrier: water-based solution with benzyl alcohol (1%) as the preservative.

3. Is L-Carnitine a peptide or a supplement?

No. L-carnitine is a single small molecule, a quaternary ammonium hydroxy acid, with no peptide bonds. It is supplied as a research solution, not as a supplement.

4. What are the CAS number and PubChem CID of L-carnitine?

PubChem lists L-carnitine as CID 10917 with CAS 541-15-1, formula C7H15NO3, molecular weight 161.20 g/mol and InChIKey PHIQHXFUZVPYII-ZCFIWIBFSA-N; ChEBI lists it as CHEBI:16347.

5. What does “L-carnitine inner salt” mean?

L-carnitine has a permanently charged quaternary ammonium group and a carboxylate, so at neutral pH it exists as a zwitterion, or inner salt. PubChem lists it as CID 10917 (C7H15NO3, 161.20 g/mol).

6. What is the difference between L-carnitine and D-carnitine?

They are enantiomers. L-carnitine is the (R)-enantiomer (ChEBI:16347), the form used by the carnitine palmitoyltransferases (McGarry & Brown, 1997); this product is L-carnitine.

7. Is the 600 mg/mL concentration verified?

The FreedomDiagnostics certificate for lot BX-A-D3L6 lists a net content of 601.79 mg/mL against the 600 mg/mL formula in the manufacturing formula.

8. How is L-carnitine made biologically?

From 6-N-trimethyllysine released by protein turnover, through four enzymatic steps ending at γ-butyrobetaine hydroxylase (Vaz & Wanders, 2002).

9. How does L-carnitine compare to acetyl-L-carnitine?

Acetyl-L-carnitine is the acetyl ester formed by carnitine acetyltransferase (Ramsay & Naismith, 2003); L-carnitine is the free carrier. Acetyl-L-carnitine appears in the Carnosine + Carnitine Based Amino Blend, while this product is L-carnitine alone.

10. What format is L-Carnitine supplied in?

One format: a 20 mL vial of solution at the per-mL amounts listed above. The vial label lists the per-mL ingredients, and the Certificate of Analysis tab lists the certificates for the current format.

11. How does Modern Aminos verify L-Carnitine?

The FreedomDiagnostics certificate for lot BX-A-D3L6 lists LC-MS identity (carnitine), HPLC-UV purity of 99.69%, net content of 601.79 mg/mL and a PCR microbial screen (no detectable microbial DNA). The finished format also lists a USP <71> sterility pass from Vanguard Laboratory (5/29/2026). For background on chromatographic testing, see why HPLC testing matters.

12. How should L-Carnitine be stored in the lab?

Keep the sealed vial cool, dry and away from light, and follow the label on each lot. No storage temperature is printed on the label or the certificates, so this page does not state one.

DISCLAIMER: All compounds and research materials supplied by Modern Aminos are intended exclusively for in vitro laboratory research by qualified professionals. They are not medicinal products and have not been authorised by the European Medicines Agency or any national competent authority for human or veterinary use. They are not foods, food supplements, cosmetics or medical devices. Products must not be administered to humans or animals by any route and must not be used for in vivo experimentation or any other non-laboratory purpose. We will refuse or cancel orders, and may close accounts, where there is any indication of human or animal use. By purchasing, you confirm that products will be used only in a controlled laboratory environment by appropriately qualified personnel, in line with all applicable laws.

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Disclaimer!

All products are sold in powder (lyophilized) form and require reconstitution with a suitable diluent for research purposes only. Research supplies (e.g., syringes, bacteriostatic water) are not included. No dosing instructions are provided. We adhere to all local and state laws around Research Only Chemical sales. We are not a pharmacy, nor do we promote or provide any advice for human or animal consumption. Please review our terms and conditions carefully before making a purchase on our website.

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